Shirnk-Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives
A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment “wrinkles”. Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.
Text ReferenceAaron Chen, Deborah Lieu, Lauren Freshauf, Valerie Lew, Himanshu Sharma, Jianxian Wang, Diep Nguyen, Ioannis Karakikes, Roger Hajjar, Ajay Gopinathan, Elliot Botvinick, Charless Fowlkes, Ronald Li, and Michelle Khine. Shirnk-film configurable multiscale wrinkles for functional alignment of human embryonic stem cells and their cardiac derivatives. Advanced Materials, 23:5785–5791, 2011.
AUTHOR = "Chen, Aaron and Lieu, Deborah and Freshauf, Lauren and Lew, Valerie and Sharma, Himanshu and Wang, Jianxian and Nguyen, Diep and Karakikes, Ioannis and Hajjar, Roger and Gopinathan, Ajay and Botvinick, Elliot and Fowlkes, Charless and Li, Ronald and Khine, Michelle",
TITLE = "Shirnk-Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives",
JOURNAL = "Advanced Materials",
YEAR = "2011",
VOLUME = "23",
ISSUE = "48",
PAGES = "5785-5791",
TAG = "biological_images"