Shrink-Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives
Abstract
A biomimetic substrate for cell-culture is fabricated by plasma treatment of a
prestressed thermoplastic shrink film to create tunable multiscaled alignment
“wrinkles”. Using this substrate, the functional alignment of human embryonic
stem cell derived cardiomyocytes is demonstrated.
Cite
@article{shrink-film-configurable-multiscale-wrinkles-for-functional-alignment-2011,
author = {Aaron Chen and Deborah Lieu and Lauren Freshauf and Valerie Lew and Himanshu Sharma and Jianxian Wang and Diep Nguyen and Ioannis Karakikes and Roger Hajjar and Ajay Gopinathan and Elliot Botvinick and Charless Fowlkes and Ronald Li and Michelle Khine},
title = {Shrink-Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives},
journal = {Advanced Materials},
volume = {23},
pages = {5785-5791},
year = {2011},
doi = {10.1002/adma.201103463},
url = {https://doi.org/10.1002/adma.201103463},
}